The purpose of the research was to investigate possible links of aluminum concentrations in drinking water, and the onset Alzheimer’s disease. The cause for Alzheimer’s disease is not known. Aluminum has been tested, and proven to be toxic in the brain causing neuronal death. Previous studies that were conducted with aluminum containing products were not conclusive in showing a correlation between aluminum and Alzheimer’s disease.
The group involved in this study is known as the “Paquid cohort” which consists of 3,777 individuals 65 or older in 75 random locations in France. All individuals in the Paquid cohort where screened for dementia, and Alzheimer’s disease before data collection began. Individuals who had dementia in the initial evaluation were excluded from the test, and 703 individuals died, or refused the follow-up evaluation. The follow-up evaluation was performed on 2,698 individuals, and those individuals were used to obtain statistical data.
To measure the exposure to aluminum, each water supply was tested. Past studies by the sanitation administration were also used to evaluate previous exposure to aluminum. Areas without data were excluded from the test. This study used a total of 70 areas where measurements were available.
Results show that there is a higher risk of Alzheimer’s disease associated with a higher concentration of aluminum in drinking water. Statistically the results showed a weak correlation between aluminum, and Alzheimer’s, but the results did show a significant correlation to an increased risk of dementia. Error could have occurred in the mental evaluation of individuals in the study causing skewed results.
Rondeau, J, Commenges, D, Jacqmin-Gadda, H, & Dartigues, J. (2000). Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study. American Journal of Epidemiology, 152(1), 55-66.