Inducing remission in people
with ulcerative colitis
A NICE pathway brings together all NICE guidance, quality
standards and materials to support implementation on a specific
topic area. The pathways are interactive and designed to be used
online. This pdf version gives you a single pathway diagram and
uses numbering to link the boxes in the diagram to the associated
recommendations.
To view the online version of this pathway visit:
http://pathways.nice.org.uk/pathways/ulcerative-colitis
Pathway last updated: 24 March 2015. To see details of any updates to this pathway since its launch,
visit: About this Pathway. For information on the NICE guidance used to create this path, see:
Sources.
Copyright © NICE 2015. All rights reserved
NICEPathways
Pathways
Inducing remission in people with ulcerative colitis
Ulcerative colitis pathway
Copyright © NICE 2015.
NICE Pathways
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NICE Pathways
Inducing remission in people with ulcerative colitis
1
Person with active ulcerative colitis
No additional information
2
Mild to moderate and subacute ulcerative colitis
Severity of ulcerative colitis
In this pathway, the categories of mild, moderate and severe are used to describe ulcerative
colitis:
In adults these categories are based on the Truelove and Witts' severity index (see table 1).
In children and young people these categories are based on the Paediatric Ulcerative
Colitis Activity Index (PUCAI) (see table 2).
Table 1 Truelove and Witts' severity index
Mild
Moderate
Severe
6 or more plus at least one of the
features of systemic upset (marked
with * below)
Bowel movements
(no. per day)
Fewer than 4
Blood in stools
No more than
Between
small amounts of mild and
blood
severe
Visible blood
Pyrexia
(temperature
greater than
37.8°C)*
No
No
Yes
Pulse rate greater
than 90 bpm*
No
No
Yes
Ulcerative colitis pathway
Copyright © NICE 2015.
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