Suggested textbooks
1. An introduction to Medicinal Chemistry, third edition, Graham L. Patrick, Oxford
2. The Organic Chemistry of Drug Design and Drug Action. Richard B. Silverman, Academic Press.
3. Introduction to the Principles of Drug Design and Action. Smith and William, Harvard Academic Publishers.
Major topics (they may be presented in a different order)
1. Drug discovery, design, development and safety
2. Drug handling by the body
3. Receptors
4. Catalytic receptors
5. Enzyme inhibition and inactivation
6. Prodrugs and drug delivery systems
Evaluation
Midterm examination #1 (October 1, 2008, class hours) 25% No makeup*
Midterm examination #2 (November 5, 2008, class hours) 30% No makeup*
Final examination (exam slot 18, December 12, 2008, 12:00) 45%
* Examinations
If students do not clearly understand any questions, please ask right away. There is no re-marking, based on any misunderstanding of any questions. Every examination book will be evaluated and marked based on the same marking scheme. The marking scheme can be viewed along with the marked examination book, upon request.
1. Midterm examinations (in class time, October 1, 2008 and November 5, 2008)
a. There is no make up midterm examination.
b. If students have medical or urgent conditions that do not permit attendance of the midterm examination, an appropriate document is needed within 48 hour.
c. With the approval of the document, students will be allowed to write the final examination of which the mark is calculated to the sum of midterm and final examination marks).
2. Final examination (Registrar has assigned the exam slot, please check the location)
a. Students are allowed to bring a non-programmable calculator.
b. No cell-phone allowed.
c. Subject of an open-book examination will be discussed among students, two weeks prior to the examination date.
Rules and...