- Submitted By: Gideon-Nyakundi
- Date Submitted: 05/13/2016 4:37 AM
- Category: Philosophy
- Words: 2338
- Page: 10

Lesson 14

Confidence Intervals of

Odds Ratio and

Relative Risk

Lesson 14 Outline

Lesson 14 covers

Confidence Interval of an Odds Ratio

Review of Odds Ratio

Sampling distribution of OR on natural log scale

95% Confidence Interval of OR example

Confidence Interval of Relative Risk

Review of Relative Risk

Sampling distribution of RR on natural log scale

95% Confidence Interval of RR example

PubH 6414 Lesson 13

2

Review: Odds Ratio and Relative

Ri k

Risk

Both Odds Ratio and Relative Risk are

measures of association (or relationship)

between two nominal variables

variables.

The Odds Ratio is typically estimated from

data collected in a Case

Case--Control study

study.

The Relative Risk can be estimated from

d t collected

data

ll t d iin a prospective

ti study.

t d

PubH 6414 Lesson 13

3

Associations between 2 nominal

variable

i bl

If there is no association between the two

variables,

i bl

th

the OR or RR = 1

An OR or RR > 1.0 or < 1.0 indicates a possible

statistical

t ti ti l relationship

l ti

hi ((or association)

i ti ) b

between

t

the two variables.

Hypothesis tests for the OR and RR are not used

to determine statistical significance of the

association

Instead, Confidence intervals of OR or RR are

constructed and used to determine whether or not

the association is statistically significant.

PubH 6414 Lesson 13

4

Confidence Interval

off Odd

Odds Ratio

R ti

Review: Odds Ratio

Odds of an event =

probability that the event occurs

probability that the event does not occur

Odds Ratio

odds of event for g

group

p1

odds of event for group 2

PubH 6414 Lesson 13

6

Review: Disease OR for ‘Exposed’

compared

d to

t ‘Not

‘N t Exposed’

E

d’

Exposed Group

Not Exposed

Group

Disease

No Disease

Total

a

c

b

d

a+b

c+d

Odds of Disease for Exposed = a/(a+b) b/(a+b) = a/b

Odds of...

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