Literature Review
Human Papillomavirus
Gardasil
By
Wanda F. Carter
February 15, 2007
Table of Contents
Human Papillomavirus…………………………………………………………………………..…3
Background……………………………………………………………………………..…3
Risk Factors for HPV…………………………………………………………………………..…..4
Economical Disease Burden of HPV…………………………………………………………..….5
Reducing the Burden of HPV…………………………………………………………..…6
Gardasil Vaccine………………………………………………………………………………..….6
Dosing and Administration………………………………………………………………..7
Adverse Reactions……………………………………………………………….………..7
Efficacy……………………………………………………………………………………..…...…8
.
Long-Term Effectiveness…………………………………………………………..……..8
Other Subpopulations……………………………………………………………………..9
Policy………………………………………………………………………………...........9
Gaps……………………………………………………………………………………………....10
Recommendations……………………………………………………………..…………10
References……………………………………………………………………………..…12
Literature Review: Human Papillomavirus (HPV)
Background
Genital human papillomavirus (HPV) infection is a sexually transmitted disease (STD) which, according to the Centers for Disease Control and Prevention (CDC), is the leading cause of cervical cancer (2006). The Human papillomavirus includes more than 100 different strains or types, and more than 30 of these viruses are sexually transmitted, they can infect the genital area of either gender including the skin of the penis, vulva, anus, and the linings of the vagina, cervix, or rectum. According to the CDC approximately 20 million people are currently infected with HPV. There is no "cure" for HPV infection. The surest way to eliminate risk for genital HPV infection is to refrain from any genital contact with another individual (2006).
Human papillomavirus (HPV) is highly prevalent, and the most common newly acquired sexually transmitted infection (STI) in the United States (Cox, 2006). HPV is responsible for significant morbidity and mortality. It is estimated by the CDC that...