Q-ProAmatine® (midodrine hydrochloride) is indicated for the treatment ofsymptomatic orthostatic hypotension (OH). Becaus (midodrine hydrochloride) can cause marked elevation of supine blood pressure (BP > 200 mmHg systolic), it should be used in patients whose lives are considerably impaired despite standard clinical care, including non-pharmacologic treatment (such as support stockings), fluid expansion, and lifestyle alterations.
Q-ALPHAGAN® P (brimonidine tartrate ophthalmic solution) 0.1% or 0.15% is an alpha adrenergic receptor agonist indicated for the reduction of elevatedintraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Q-Use of carbachol, as well as all other muscarinic receptor agonists, is contraindicated in patients with asthma, coronary insufficiency, gastroduodenal ulcers, and incontinence. The parasympathomimetic action of this drug will exacerbate the symptoms of these disorders.
Q-Naphazoline is contraindicated in conditions like Asthma, Diabetes mellitus, Narrow-angle glaucoma.Q-Catapres (clonidine) tablets should not be used in patients with known hypersensitivity to clonidine.Q-Dobutamine is contraindicated in patients with idiopathic hypertrophic subaorticstenosis and in patients who have shown previous manifestations of hypersensitivity to dobutamine.Q-Silodosine:Severe renal impairment, severe hepatic impairment, coadministration with strong CYP3A4 inhibitors (eg, clarithromycin, itraconazole, ketoconazole, ritonavir).Muscarinic agonists such as cevimeline bind and activate the muscarinic M1 and M3 receptors. The M1 receptors are common in secretory glands (exocrine glands such as salivary and sweat glands), and their activation results in an increase in secretion from the secretory glands. The M3 receptors are found on smooth muscles and in many glands which help to stimulate secretion in salivary glands, and their activation generally results in smooth muscle contraction and increased...