Rhabdomyolysis

Rhabdomyloysis is caused by mechanisms that affect muscles metabolism and muscle membrane integrity. It also involves injury to the kidney and by toxic effects of the contents of muscle cells. This muscles disease if not treated appropriately can become life threatening and cause many complications such as kidney failure, hyperkalaemiaa, and can lead to a heart attack. Rhabdomyloysis is the breakdown of muscle fibers resulting in the release of muscle fiber contents. Some of these contents are toxic to the kidney and results in kidney damage. Injury can be from physical damage to the muscle. Unnecessary muscle exercise, electric shock, lighting stroke, and heat stroke can be causes of Rhabdomyloysis. Other causes are crush injury, overexertion, alcohol abuse, and certain medications. As well as some several inherited genetic disorders, such as Mcardles disease and Muscular Dystrophy. Some believe that even prescription drugs can cause Rhabdomyloysis. Even drug-induced Rhabdomyloysis is more common today than in the past. Some drugs in question are cholesterol lowering drugs, crestor, gemfibrozilm, PCP, acetyl cholinesterase inhibitors, and overdoses of heroin. Also Myoglobin which can break down into toxic compounds can cause kidney failure. Myoglobin is “an oxygen-binding protein pigment found the skeletal muscle”. When the muscles are damaged it is released in the bloodstream, filtered out by the kidneys. This can lead to the break down of the toxic compounds and reduce blood flow to the kidney and may lead to shock. This disorder is resulted in any damage to skeletal muscle especially trauma.
In diagnosing Rhabdomyloysis the doctor performs several tests, most being urine and blood tests. Tea-colored urine is usually the first symptom of Rhabdomyloysis. Other symptoms are dark, red urine, muscles tenderness, weakness of affected muscles, muscle stiffness or aches, unintentional weight gain, seizures, joint pain and fatigue....